References

The fantastic background patterns on the home page and throughout this site were taken from the following web site put out by Ken Musgrave: http://www.seas.gwu.edu/faculty/musgrave/. It has other really cool things as well. Highly recommended. The Alzheimer's Association Web Site at "http://www.alz.org/Welcome.html" Berkow, Robert-editor in chief. The Merck Manual of Diagnosis and Therapy-16th edition. Merck Research Laboratories, 1992. pp. 1403-1407. Brandt, J., Carson, K.A., Folstein, M.F., Kawas, C., Rasmusson, D.X., & Rich, J.B., :Non-steroidal anti-inflammatory drugs in Alzheimer's disease," Neurology vol. 45, no. 1, Jan 1995. Breitner, J.C., "The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease," Annual Review of Medicine vol. 47, 1996. Brodie, J.D., Dewey, S.L., Logan, J., & Smith, G.S., "Modulation of central cholinergic activity by GABA and serotonin: PET studies with 11C-benztropine in primates," Neuropsychopharmacology, vol. 8, no. 4, Jun 1993. Butterfield, D.A., Carney, J.M., Harris, M.E., Hensley, K., Pedigo N.W., & Wang, Y., "Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampul astrocyte cultures," Neurochemistry, vol. 67, no. 1, Jul 1996. Christine, D., Cummings, J.L., & Kaufer, D.I., "Effect of tacrine on behavioral symptoms in Alzheimer's disease: an open-label study," Geriatrics of Phsychiatry and Neurology, vol.9, no. 1, Jan 1996. Coyle, Joseph T. Edited by George Adelman in Encyclopedia of Neuroscience. Birkhauser, 1987. pp 29-31. Davies, K.J., "Oxidative stress: the paradox of aerobic life," vol. 61, 1995. Dunnett, S.B., Everitt, B.J., Muir, J.L., & Robbins, T.W., "Attentional functions of the forebrain cholinergic systems: effects of intraventricular hemicholinium, physostigmine, basal forebrain lesions and intracortical grafts on a multiple-choice serial reaction time task," Experimental Brain Research, vol. 89, no. 3, 1992. Giles, Kurt, Web site at "http://bnstb.bio.bnl.gov:8000/disk$3/giles/che.html" Glenner, George C. Encyclopedia of Human Behavior, Volume I. Academic Press, Inc. 1994. Pages 103-111. Kaufman, Mavis A. Edited by Benjamin B. Wolman in International Encyclopedia of Psychiatry, Psychology, Psycholanalysis and Neurology. Aesculapieus Publishers, Inc., 1977. pp. 439-441. Levin, E.D., Rose, J.E., "Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze," Brain Residue Bulletin, vol. 27, no. 1, Jul 1991. McGeer, E.G., & McGeer, P.L., "Anti-inflammatory drugs in the fight against Alzheimer's disease," vol. 777, Jan. 17, 1996. Small, David. Web site at "http://werple.mira.net.au/~dhs/ad.html". The Alzheimer Web: Devoted to Research on Alzheimer's Disease. Images of the normal brain, the atrophied Alzheimer's brain, and amyloid plaques and tangles were taken from the following University of Utah-Salt Lake City web site:"http://www-medlib.med.utah.edu/WebPath/CNSHTML/CNSIDX.html". It's a great link for neuropathology images. Reference sites used for the Genetics page:

Edland SD; Silverman JM; Peskind ER; Tsuang D; Wijsman E; Morris JC. "Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal nheritance." Neurology (NZ0), 1996 Jul; 47 (1): 254-6. Lautenschlager NT; Cupples LA; Rao VS; Auerbach SA; Becker R; Burke J; Chui H; Duara R; Foley EJ; Glatt SL; Green RC; Jones R; Karlinsky H; Kukull WA; Kurz A; Larsen EB. "Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?" Poirier J; Minnich A; Davignon J. "Apolipoprotein E, synaptic plasticity and Alzheimer's disease." Ann Med (AMD), 1995 Dec; 27 (6): 663-70. Rao VS; Cupples A; van Duijn CM; Kurz A; Green RC; Chui H; Duara R; Auerbach SA; Volicer L; Wells J; van Broeckhoven C;Growdon JH; Haines JL; Farrer LA. "Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4." Am J Hum Genet (3IM), 1996 Sep; 59 (3): 664-75. Rao VS; van Duijn CM; Conner-Lacke L; Cupples A; Farrer LA. " Multiple Etiologies for Alzheimer Disease Are Revealed by Segregation Analysis." Am.J.Hum. Genet., 1994 55, 991-1000. Roses AD. "Apolipoprotein E alleles as risk factors in Alzheimer's disease." Annu Rev Med (6DR), 1996; 47 387-400. Roses AD; Einstein G; Gilbert J; Goedert M; Han SH; Huang D; Hulette C; Masliah E; Pericak-Vance MA; Saunders AM; Schmechel DE; Strittmatter WJ; Weisgraber KH; Xi PT. "Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism." Ann N Y Acad Sci (5NM) 1996 Jan 17; 777 146-57. . Tang MX; Maestre G; Tsai WY; Liu XH; Feng L; Chung WY; Chun M; Schofield P; Stern Y; Tycko B; Mayeux R. "Relative risk of Alzheimers disease and age-at-onset distributions, based on APOE genotypes among elderly African Caucasians, and Hispanics in New York City." Am J Hum Genet (3IM), 1996 Mar; 58 (3): 574-84 Reference sites used for the Estrogen page:

Birge, S.J., (1996). "Is there a role for estrogen replacement therapy in the prevention and treantment of dementia?" Journal of American Geriatric Society, 44, 860-870. Hagino, N., (1994). "Estrogen in cognetive behaviors - Clinical application of estrogen for dementia of alzheimer type." Acta Biologica Hungarica, 45, 233-247. Ohkura, T., Isse, K., Akazawa, K., Hamamoto, M., Yaoi, Y., Hagino, N., (1994). "Evaluation of estrogen treatment in female patients with dementia of the alzheimer type." Endocrine Journal, 41, 361-371. Ohkura, T., Isse, K., Akazawa, K., Hamamoto, M., Yaoi, Y., Hagino, N., (1995). "Long-term estrogen replacement therapy in female patients with dementia of the alzheimer type: 7 case reports." Dementia, 6, 99-107. Paganini-Hill, A., (1996). "Estrogen Replacement therapy in the elderly." Zentralbl Gynakol, 118, 255-261. Sherwin, B.B., (1996). "Hormones, moods, and cognitive Functioning in postmenopausal women." Obstetrics & Gynecology, 87 (supplement), 20s-26s. Stephenson, J., (1996). "More evidence links NSAID, estrogen use with reduced Alzheimer risk" [news]. JAMA, 275, 1389-1390. Tang, M.X., Jacobs, D., Stern, Y., Marder, K., Schofield, P., Gurland, B., Andrews, H., Mayeux, R., (1996). "Effects of oestrogen during menapause on risk and age at onset of Alzheimer's disease." Lancet, 348, 429-432.

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