- Jan 30 Opening conversation for "The Soul Selects her own Society: Women Artists from the Miller Meigs Collection"
- Feb 3 Taste of Service
- Feb 3 Macalester New Music Series presents INTERSECTION: Jazz Meets Classical Song
- Feb 4 'Moving Beyond Minnesota Nice:' Engaging Diversity in the Classroom
- Feb 12 Mitau Lecture
- Feb 17 Black History Month Keynote: Dr. Joy DeGruy - "Post-Traumatic Slave Syndrome"
- Feb 18 Mental Health Awareness Film & Speaker
- Feb 19 The Inaugural Lecture of James Dawes as DeWitt Wallace Professor of English
- Feb 19 Robert Blanchette on "Tombs, sunken ships and historic huts: studying ancient wood reveals secrets from the past"
- Feb 19 Chamber Music at Macalester: Brahms Clarinet Quintet with Osmo Vanska
My interest was sparked in genetics class when Professor Mary Montgomery described RNA interference (RNAi), a Nobel prize-winning discovery that she participated in as a post-doctorate. RNAi is a pathway through which double-stranded RNA can inhibit gene expression. I was fascinated by the complexity and excited to investigate the regulation of genes through RNAi by working with Professor Montgomery.
The human genome contains many repeated genes that must be silenced so that they do not insert into other genes and cause diseases. Human genetics is complex, so it is helpful to gain a basic understanding of silencing mechanisms by studying other organisms.
In Professor Montgomery’s lab we worked with microscopic worms, Caenorhabditis elegans. Experiments are conducted using strains of C. elegans carrying green fluorescent protein (GFP) genes. In strains carrying a single GFP gene, the C. elegans germ line glows green under fluorescent light. However, in a strain possessing multiple copies of the GFP gene on another chromosome, no fluorescence is observed.
I forged new connections with my co-workers as part of a research team and in the span of 10 weeks, I learned to use new equipment, design experiments, evaluate data and troubleshoot problems, all under the guiding hand of an experienced researcher.