

Current treatments include psychotherapy, tricyclic antidepressants, traditional monoamine oxidase inhibitors (MAOIs), and benzodiazepines. The classic MAOI's are effective, but have very low rates of compliance because of the severe dietary restrictions that accompany their use. For this reason researchers have explored the use of reversible and selective MAO-A inhibitors in the treatment of panic disorder. They are effective in the treatment of depressive illness, and produce minimum side effects. Garcia-Borregueuro et al. studied the effects of brofaromine, one of the reversible and selective MAO-A inhibitors, on patients with panic disorder. The results of this study proved brofaromine to have a statistically significant superior effect over the placebo.

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