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MAOIs are often used on patients vulnerable to depression but who don't suffer from the classic symptoms of major depression. They are especially good for mild depression, or when the onset of depressive symptoms is more gradual, when primary complaints are of boredom and apathy.
MAOIs are often used for those patients with atypical depression, those with extreme sensitivity to rejection, prone to overeating and oversleeping, and those with "overly" strong reactions to the environment. MAOIs can serve to reduce this extreme sensitivity, reducing symptoms of depression.
Who Shouldn't Take MAOIs
MAOIs can be of particular danger to those with serious heart problems, epilepsy, bronchitis, asthma, or high blood pressure. Their use also requires following a stringent diet (see side effects page), therefore an ability to do so is mandatory.
For those who are hyperactive, agitated, or schizophrenic, isocarboxazid, another MAOI, may be too stimulating. Studies suggest that Nardil may not be as effective for those who are severely depressed. Patients should wait at least two weeks when being transferred to Parnate from another MAO inhibitor.
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