SSRIs:Potential Side Effects


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General Note:

Just about everything imaginable has been reported in people taking SSRIs. Most patients complain of only a few if any side-effects. The intended effects may take 2-6 weeks to onset.






The most common side effects are "gastro-intestinal", ie: feeling sick, vomiting, indigestion, abdominal pain, diarrhea or constipation which generally lasts only a few days.
Other side effects can include:

  • Loss of appetite; weight loss.
  • Increased appetite; weight gain.
  • Allergic reactions.
  • Dry mouth
  • Irritability/anxiety
  • Sleeplessness
  • Drowsiness
  • Headache
  • Shaking
  • Dizziness
  • Fits/convulsions
  • Disturbance of sexual function (yet this is also a feature of depression)
  • Sweating
  • Bruising
  • Manic or hypomanic behavior
  • Abnormal movements
  • Low sodium level
  • Impaired performance of tasks requiring skill and coordination

Other things to keep in mind:

  • Researchers note that the SSRIs don't work for 20 to 40 percent of depressed or anxious people who try them -- the same failure rate as the older antidepressants.
  • Increased suicidal thoughts and violent behaviors have been linked to young people taking antidepressants. More on this.
  • Severe kidney or liver disease could result in higher-than-normal blood levels of the SSRIs.
  • Always remember to tell the doctor if you are allergic to anything.
  • SSRIs shoul not be stopped suddenly. Discuss stopping them with your doctor. (This is usually after 3-6 months)
  • A major advantage of SSRIs is that they are not so dangerous if someone takes an overdose.