More Info About Clozapine (Clorazil)
General info
Clozapine
was the first antipsychotic drug to be considered“atypical". It
was
synthesized in 1960 and its first clinical trial was completed in 1962.
U.S. marketing began in
February 1990, whereas in Europe it
was made available for clinical use in 1975. It
is
part of the
dibenzodiazepine class of antipsychotics. In the US ,
clozapine is only approved for
the treatment of patients with that have not responded to previous
treatment
with typical drugs (e.i. treatment-refractory patients) . Patients
treated with clozapine have been able to sustain more independent
lives
than other treatment-refractory patients whose condition has not
been improved by other treatments (Perry 2001).
Side
Effects of
Clozapine