SSRIs: Introduction

Selective Serotonin Re-uptake Inhibitors (SSRIs) are a relatively recent category of drug primarily used to treat depression. Older antidepressants act primarily through the dopamine and norepinephrine pathways.

SSRIs, which act on serotonin, were developed in the 1970ís with the hope that they would have far fewer side effects then already existing antidepressants. They became wildly successful on the market and remain popular today.